Molecular Histology for JOH in 2019

By: Yongfu Wang

With the development of the histotechnology profession, many academic journals were established to create platforms for communicating new findings, educating others and advancing the field. The Journal of Histotechnology (JOH), the official journal of the National Society for Histotechnology (NSH), is proud to be one of those journals with a continuous 42-year publication history.

As a relatively new NSH member, I am always grateful for our pioneer histotechnicians, as well as the leaders who volunteered their efforts and provided a vision to establish NSH and its official academic journal, JOH. We all understand the important achievements that JOH has made in the past for NSH members. JOH not only provided an educational platform for members, but also served as a communication tool for histotechnicans, giving a voice to what we did and how we promoted science through basic research and humanity via patient care. With NSH and JOH, we all connect with each other and with the public from behind the scenes.

I was humbled to be nominated as an Associate Editor of JOH in early 2018. As an editorial board member, I cheer for all milestones that JOH has achieved. Our Journal has been indexed by many reputable organizations including Thomson Reuters - Science Citation Index Expanded (SCIE), Scopus, Global Health, Chemical Abstracts and many others. By 2018, JOH had published 41 volumes, with many papers distributed internationally. The teamwork by NSH Board of Directors, NSH office, JOH Editorial Board, the publisher, NSH members and authors from the U.S and abroad, have gotten JOH this far.

As part of its success in the past, JOH published special editions themed on various topics, from fixation to neuronal diseases. By working with our Interim Editor-in-Chief, Gayle Callis, Executive Director, Sharon Kneebone, NSH president, Diane Sterchi, and publisher, Taylor and Francis, an upcoming JOH special edition on molecular histology will be launched, with a submission due date of April 1st, 2019.

When planning the 2019 special edition, we wanted a theme on useful, powerful and new technologies in our field. Enlightened by Dr. Richard W. Cartun’s argument in his JOH editorial article (Cartun, 2002) that “the sign of a useful and powerful technology is its continued use over time”, we picked immunohistochemistry and in situ hybridization topics to resume publishing a JOH special edition. Seventeen years have passed since Dr. Cartun wondered if immunohistochemistry “is still being used in diagnostic pathology laboratories in the year of 2027”. It is obvious that both immunohistochemistry and in situ hybridization techniques are still going strong and getting stronger. Therefore, JOH can certainly do another special edition on this topic. We hope some of following topic aspects used by both clinical and research laboratories will be covered in the 2019 special issue

  • Antibody validation

  • Antibody searching tools

  • Expanded application of existing antibodies on uncommonly used animal models

  • Single-domain antibodies for super-resolution imaging

  • Metal-conjugated antibodies to combine immunostaining with mass spectrometry or electron microscopy.

  • Helpful tips for using immunohistochemistry assay on problematic tissues.

  • Single molecule in situ hybridization such as RNAScope, BaseScope, hybridization chain reaction, Stellaris, and ClampFISH.

  • Combining single molecule in situ hybridization with validated immunohistochemistry assay on a same section.

If interested in submitting to this special issue, click here to learn more.


Cartun R. Editorial: Immunohistochemistry - 25 years and still going strong. J Histotechnol. 2002; 25:181

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